Hungarian Centre of Excellence
for Molecular Medicine
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HCEMM-USZ Functional Cell Biology
and Immunology
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HCEMM-BRC Single Cell Omics
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HCEMM-SU In Vivo Imaging
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Description

of the tools

The molecular imaging laboratory offers a wide array of quantitative measurements in live animals.

PET and SPECT systems are serving femtomolar sensitivity isotope-based methods. The very high sensitivity of PET and SPECT are complemented by anatomic measurements of MRI and CT. Protein expression and organ-specific fluorescence are measured deep in intact tissues using our unique Short-wave infrared fluorescence system. Stroke-related blood flow changes in turn, are quantified with a ultra-resolution ultrasound device. Radiochemical and nanoparticle laboratories are integrated to the whole animal imaging workflow. We can serve the needs of cardiology translational research groups from synthesis to radiomics-based image data analysis.

Our hardware is complementing a very experienced team with a decade of international collaborations.

Mediso nanoScan® PET/MRI 3T: Full-scale, quantitative PET combined with a robust, cryogen-free 3 Tesla MRI, resolution of PET 0.3 mm, MR resolution 50 microns.

Mediso nanoScan® SPECT/CT: absolute quantification and full stationary dynamic ECG-gated imaging down to 0.3 mm in vivo resolution of SPECT and 10 microns of CT.

Mediso nanoScan® 1T MRI: High soft tissue contrast, cost-effective solution. The compact system with high-performance magnet is optimized to perform fast (seconds to minutes) routine studies with high resolution (100 microns) of soft tissue contrast.

Iconeus One: This is the first and only fully-featured acquisition system for pre-clinical brain activity and vasculature functional ultrasound (fUS). 15 MHz and 3 micron resolution.

IR VIVO™ – NIR-II: Preclinical Imager is an infrared multispectral system for small animal studies, unique in Europe offering real tissue penetration infrared fluorescent images in the whole mouse depth.

FOBITM fluorescence system: for an affordable and very reliable full range visible fluorescent imaging result.

Software

Mediso Fusion full suite of image analysis and image co-registration. GeoFract software of geometric parameter and fractal analysis on images. We also have access to OLINDA radioactive dosimetry software.

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